The answer is E) variant Creutzfeldt-Jakob disease.
Explanation:
Transmissible Spongiform Encephalopathies are a group of degenerative pathologies of the central nervous system, which can be transmitted to man by eating contaminated meat. When contaminated meat comes from cattle, the disorder is called Creutzfeldt-Jakob disease, which leads to dementia and death. The disorder is rare.
The disease is characterized by accelerated mental deterioration, usually after a few months. Most people usually go into a coma.
Without options my best guess would be sybtomps would groe over time from childhood all the way to adulthood but the severity if the depreisson is not a givin fact and can from mild to MDD.