You could say something along the lines of:
"Hey, Friend, what's so good about weed? Why are you always smoking it?"
If he's smoking it for medical purposes, then just drop it, but if it's illegal and he's doing it to "look cool", then I would further ask questions about it.
What are the different answers?
Cholesterol (especially LDL*) tend to get into macrophages which migrate into blood vessels. Macrophages with cholesterol cannot get out of the vessels and stay there which causes a lipid mass in arteries. That causes atherosclerosis.
Any child born at 36 weeks or earlier is considered premature.
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