Single-cell RNA-sequencing (scRNA-seq) provides the chance to analyze heterogeneous cellular compositions and probe the patterns of gene expression that are unique to each cell type under various circumstances. However, batch effects like lab setups and individual variability make it difficult to use them in cross-condition designs.
<h3>What is Single-cell transcriptomes ?</h3>
In single-cell transcriptomics, the messenger RNA levels of hundreds to thousands of genes are simultaneously measured to assess the degree of gene expression in individual cells within a particular population.
<h3>Advantages : </h3>
• Integrated protocol proceeds directly from whole cells and preserves sample integrity.
• High resolution analysis enables discovery of cellular differences typically hidden by bulk sampling methods.
• Robust transcriptome analysis down to single-cell input levels for high-quality samples.
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Answer;
-During the process of cellular respiration, the energy stored in glucose is transferred to ATP.
Explanation;
-During Cellular Respiration, sugar is broken down to CO2 and H2O, and in the process, ATP is made that can then be used for cellular work.
-During this process, the energy stored in glucose is transferred to ATP. Energy is stored in the bonds between the phosphate groups (PO4-) of the ATP molecule.
-Energy is then liberated from the ATP molecule to do work in the cell by a reaction that removes one of the phosphate-oxygen groups, leaving adenosine diphosphate (ADP). When the ATP converts to ADP, the ATP is said to be spent.
The statement that may explain type II diabetes is that a protein that is normally activated by the insulin receptor does not perform its function. That is option C.
<h3>Causes of type II diabetes</h3>
Diabetes mellitus is a metabolic disorder that occurs due to the inability of the body cells to utilize the insulin produced as seen in type II diabetes or the inability of the pancreatic cells to produce insulin in enough quantity.
In type II diabetes, there is presence of insulin in the bloodstream of the patient but the body cells are not able to make use of it to metabolize glucose.
This is because when the protein that is activated by insulin receptor fails to function, problems with insulin signalling can occur which impairs the proper management of glucose levels in the blood.
Therefore, the statement that may explain type II diabetes is that a protein that is normally activated by the insulin receptor does not perform its function.
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