1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
levacccp [35]
3 years ago
15

Warfarin acts by inhibiting the activity of the VKORC1 protein, which helps to produce functional clotting factors. There is a v

ariant in the VKORC1 gene that lowers the dose of warfarin required for treatment, and individuals with this variant have increased risk of bleeding when they are treated with warfarin. This variant is found 1639 base pairs upstream of the translational start site. This variant likely:______.
a. decreases the activity of the VKORC1 protein.b. increases the activity of the VKORC1 protein.c. decreases expression of the VKORC1 gene.d. increases expression of the VKORC1 gene.
Biology
1 answer:
Andreas93 [3]3 years ago
8 0

Answer:

The correct answer - c. decreases expression of the VKORC1 gene.

Explanation:

Mutation of Guanine nucleotide into Adenosine is the reason for this particular type of mutation. This mutation expresses the less expression of the VKORC1 protein.

The mutation results in a decrease in the affinity of the binding site of the transcription factor which causes less expression. Since the VKORC1 protein is less in the body so Warfarin doses are decreased  

Thus, the correct answer is - decreases expression of the VKORC1 gene.

You might be interested in
ILL GIVE BRAINLIEST!!!
Semenov [28]

Answer:

in my opinion i think its B because it makes more sence.

3 0
2 years ago
Read 2 more answers
A neuron can receive thousands of EPSPs from different neurons, and responds by triggering or not triggering an action potential
Korvikt [17]

Answer:

The addition and response to the net effect of postsynaptic potentials is called Spatial summation

Explanation:

Signal summation occurs when impulses received by a neuron are eummed together to reach the excitation threshold to fire a neuron. It occurs at the axon hillock of a neuron. Signal summation occurs since each neuron is connected to many other neurons, often receiving multiple impulses from them, both excitatory and inhibitory.

Signal summation can either be temporal or spatial.

Temporal summation, occurs when impulses received at the same place on the neuron in close temporal succession add up to initiate an action potential in the neuron.

Spatial summation occurs when impulses received simultaneously at different places on the neuron add up to initiate an action potential in the neuron.

8 0
2 years ago
What are the end products of the HYDROLYSIS of a polysaccharide?
cricket20 [7]

Answer:

The most important polysaccharide to man. Upon complete hydrolysis will yield glucose molecules. found as a stored polysaccharide in the liver of man and other animals. This is how our bodies store sugars for later use.

Explanation:

Brainliest please?

8 0
2 years ago
Read 2 more answers
The primary neurotransmitter at the neuromuscular junction is
aleksandrvk [35]

Answer:

<u>acetylcholine</u>

Explanation:

In the pre-synaptic knob there are vesicles which contain a transmitter substance called acetylcholine. When an impulse reaches the synaptic knob, it stimulates the vesicles to move towards the pre-synaptic membrane releasing the acetylcholine.

The transmitter substance makes the membrane permeable. The neuromuscular junction contains the sensory neurone(afferent), motor neurones(efferent) and the relay neurones(connector).

5 0
3 years ago
Need help ASAP. (biology)
gavmur [86]

A MYSTERIOUS ailment has been devastating the much studied lions of the Serengeti National Park in Tanzania, and scientists said yesterday that it had been identified as canine distemper, a viral disease that causes severe neurological symptoms and death.

4 0
3 years ago
Read 2 more answers
Other questions:
  • Which of the following correctly lists the hierarchy of ecosystems? (Smallest to largest)
    13·2 answers
  • Based on the parents' genotypes, what is the genotypic ratio expected from a monohybrid cross between the two parents for the tr
    10·1 answer
  • WILL GIVE BRAINLIEST!!RATE!!VOTE!!!HELP!!!!!!!!!!!!!!!!!
    14·2 answers
  • Which of these statements about the afferent division of the nervous system is true?It ascends with sensory information.It desce
    9·1 answer
  • The best way to gain weight is to increase your _______ intake.
    12·2 answers
  • Please help this question got me confused.
    12·1 answer
  • In the past, some scientists accepted the theory of spontaneous generation. This theory states that organisms can arise from non
    10·1 answer
  • Define the photosynthesis?​
    13·2 answers
  • What might happen if the number of chromosomes within the cells did not change but new daughter cells were still made? (meiosis)
    9·1 answer
  • Connective tissue is made of which three essential components?
    6·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!