Indeed correct, and the reason is because it’s efficient, has no nuclear waste etc.
This is an experiment where the researcher manipulates one variable, and control/randomizes the rest of the variables. It has a control group, the subjects have been randomly assigned between the groups, and the researcher only tests one effect at a time.
Answer:
Explanation:
Pharmacophore (pharmacology) - The molecular framework responsible for a drug's biological activity. According to IUPAC — A pharmacophore is the ensemble of steric and electronic features that is necessary to ensure the optimal supramolecular interactions with a specific biological target structure and to trigger (or to block) its biological response.
Privileged structures are defined as molecular frameworks which are able of providing useful ligands for more than one type of receptor or enzyme target by judicious structural modifications.
1) The 1,4-dihydropyridine ring is present in many biologically important molecules that acts as an important scaffold for cardiovascular drug - a calcium antagonists and although it is technically not considered as a pharmacophore, it is considered as a privileged structure.
1,4-Dihydropyridine (DHP), belongs to the class of calcium antagonist that inhibits the influx of extracellular Ca+2 through the L-type voltage-dependent calcium channels.
A positional substitution in the 4-position is feasible in the heterocyclic ring which in turn culminates in various calcium channel antagonist activities and this heterocyclic ring is the common feature for various pharmacological activities such as anti-inflammatory activity, analgesic activity,
antihypertensive, antianginal, antitumor, antitubercular activity and antithrombotic .
Position on the heterocyclic ring binds to the L-type channel and also to N-type channel on membranes.
2.) The bioisosteres are not a suitable bioisostere for the traditional C-4 aryl or heteroaryl substitution which is necessary for calcium ion blockage thereby inhibiting it to function with the mechanism shared above.
Answer:
abiogenesis
Explanation:
a (not) biogenesis (coming from other life forms)
Biogenesis would mean that it's coming from other life forms,
Natural selection is a part of evolution (what is there to select?)
Variation is also a part of evolution (not related)
The correct answer is option B) their DNA sequences.
The best comparison for finding out the evolutionary relationship between two organism is the comparison of their DNA (deoxyribonucleic acid) sequence. The organisms, which are more closely related to one another share more similarity in the DNA sequence as compared to the distantly related organism, so, the comparison of the DNA can help in determining the evolutionary relationship between the organism.
