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Answer:
4. Pathogens enter and multiply in body tissues.
Explanation:
When pathogen penetrates the host defenses, infection occurs in the host. Infection is a disease of the body that is caused by invasion and multiplication of pathogens (infectious biological agents that causes diseases or illnesses to the host) such as bacteria, viruses, parasites and so on normally not found with the body. They can easily spread from their point of origin if not contained due to the multiplicability of the pathogens causing it.