Glycolysis may be defined as the process in which a glucose molecule is broken down into the two molecules of the pyruvate. Pyruvate is used to produce energy through various pathways that depends upon the availability of the oxygen. However when the glycolysis in blocked and the pyruvate is not formed, then the cells would not be able to use either the fermentation or aerobic respiration or the perform citric acid cycle. So the cell does not make any ATP.
