Being that it is one of the biggger and longer bones in the body i would say long
Answer and Explanation:
Ergotamine has been used for over 50 years and was the first specific drug to treat migraine attacks. Its therapeutic effect is due in part to its ability to contract the vessels. It is a vasoconstricting alkaloid used in migraine attacks, when treatment with non-steroidal anti-inflammatory drugs has no effect.
The mechanism of action of ergotamine is complex. The molecule has structural similarities to neurotransmitters such as seratonin, dopamine and adrenaline, and can therefore bind to various receptors and function as an inhibitor. Its use in the treatment of migraines is due to its vasoconstrictor effect of extracerebral intracranial blood vessels through their binding to the 5-HT1B receptor and inhibition of neurotransmitter binding.
Overuse of ergotamine may cause nausea, vomiting (to direct effects on the Central Nervous System in the vomiting centers) , malaise, headache, constriction of peripheral vessels and more severe effects such as ischemia of the extremities.
Ergotamine poisoning is called ergotism.
Ergotamine should not be used in patients with peripheral arterial or venous vascular insufficiency, ischemic heart disease, cerebrovascular disease, systemic infection and hypertension without effective control.
Answer:
Maturation change in the central nervous system
Explanation:
<em> As the child begins to develop they have a short attention spans; the ability for keeping an attention to a time.</em>
<em>The ability for having a sustainable attention improves gradually in childhood and adolescence. these improvements is called the maturation changes in the central nervous system
</em>
<em>Even when children are playing with toys, Gadgets or watching Television they are often distracted most times and their attention is becomes divided and they cannot interdict or capture irrelevant task thought processes.</em>
3.) Do not bottle-feed after you baby is 6 months old
