Transmembrane proteins are found in the plasma membrane. Hydrophilic regions are embedded
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within the membrane, and Hydrophobic regions project from both surfaces of the bilayer.
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Approximately 20-80% of the cell membrane is composed of lipids, the rest, is made up of protein. The lipid layer of the membrane gives it flexible and permeable characteristic. While the protein part assists in transport of molecules it needs to survive.<span>
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B double helix and linked with hydrogen bonds
Stereotactic radiosurgery (SRS) and immune checkpoint inhibitors (ICI) are increasingly used to treat brain metastases, however there is a paucity of prospective data on the effectiveness of these treatments in terms of cancer control.
Data from patients treated with SRS for non-small cell lung cancer (NSCLC) and melanoma brain metastases at a single facility from May 2008 to January 2017 were retrospectively examined. The impact of concurrent ICI within 30, 60, or 90 days of ICI administration on local control and remote in-brain control is examined using a parametric proportional hazard model. The regression model takes into account other patient and lesion characteristics as covariates and makes adjustments.
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DNA is made up of deoxyribose sugar while mRNa is made up of ribose sugar. DNA has thymine as one of the two pyrimidines while mRNA has uracil as its pyrimidines base. DNA is present in the nucleus while mRNA diffuses into the cytoplasm after synthesis. DNA is double stranded while mRNA is single stranded.
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