Hybridomas, which produce monoclonal antibodies, are made by fusing cells of the immune system with B lymphocytes and myeloma cells.
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What are Hybridomas?</h3>
- Large-scale production of monoclonal antibodies is made possible through hybridoma technology.
- An antigen that triggers an immune response is first injected into a mammal to begin the process.
- A specific sort of white blood cell called a B cell makes antibodies that bind to the antigen that has been injected.
- These antibody-producing B-cells are then removed from the animal and combined with immortal B cell cancer cells, or myeloma, to create a hybrid cell line known as a hybridoma.
- It possesses both longevity and procreative capacity of the myeloma and the antibody-producing capacity of the B-cell.
Hence, the creation of hybridomas, which result in the production of monoclonal antibodies, involves fusing immune system cells with B lymphocytes and myeloma cells.
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