Background- In patients with intracranial artery stenosis, a long-term advantage of dual antiplatelet therapy (DAPT) over single antiplatelet therapy (SAPT) for the prevention of recurrent stroke has not been proven. We studied patients with intracranial arterial stenosis who were enrolled in the Cilostazol Stroke Prevention Study for Antiplatelet Combination trial, a randomized controlled trial in high-risk Japanese patients with ischemic stroke, to compare the efficacy and safety of DAPT with cilostazol and clopidogrel or aspirin to those of SAPT with clopidogrel or aspirin. Techniques and Outcomes In patients with ischemic stroke with symptomatic or asymptomatic intracranial arterial stenosis of at least 50% in a major intracranial artery, we compared the vascular and hemorrhagic events between DAPT and SAPT.
Patients were divided into two groups: 275 were given DAPT, while 272 were given SAPT. In contrast to SAPT, which had a higher risk of serious or life-threatening bleeding, DAPT had a lower risk of ischemic stroke (hazard ratio [HR], 0.47; 95% CI, 0.23-0.95); and a composite of stroke, myocardial infarction, and vascular mortality (HR, 0.48; 95% CI, 0.26-0.91). Conclusions In patients with intracranial artery stenosis following stroke, DAPT using cilostazol was superior than SAPT using clopidogrel or aspirin for the prevention of recurrent stroke and vascular events without raising bleeding risk.
<h3>What is
stroke?</h3>
When anything prevents blood flow to a portion of the brain or when a blood artery in the brain bursts, a stroke, also known as a brain attack, happens. The brain either ages or suffers harm in both scenarios. A stroke may result in permanent brain damage, chronic disability, or even fatality.
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Answer:
Speech therapy and hearing aids may be required
Explanation:
Answer:
The answer is: <u>horizontal plate of</u><u> </u><u>palatine bone</u> and <u>palatine process</u> of the maxilla bone.
Explanation:
The nasal cavity is the bilateral air-filled space present above the roof of the mouth and behind the nose, that forms the interior of the nose.
The hard palate forms the roof of mouth and floor of the nasal cavity. The bones of the hard palate that are present on the <u>floor of nasal cavity </u><u>are the horizontal plate of</u><u> palatine bone</u><u> and </u><u>palatine process</u><u> of the maxilla bone.</u>
Answer:
a. I olfactory
Explanation:
Journey of the Olfactory nerve:
-Originates on the caudal surface of the olfactory bulb
-Crosses the cribriform plate of the ethmoid bone from one part of the critlal galli to the other
-Reachers the olfactory region of nasal cavity
Answer:
A) hypovolemic
Explanation:
When there is extensive bleeding, the volume of blood in the entire circulatory system decreases considerably. Therefore, the patient usually goes into hypovolemic shock.
In this type of shock the heart is unable to pump enough blood due to the large decrease in venous return. As a consequence, arterial blood pressure drops.