Mitochondria have an important role in cellular respiration through the production of ATP, using chemical energy found in glucose and other nutrients. Mitochondria are also responsible for generating clusters of iron and sulfur, which are important cofactors of many enzymes.
<span>I think the pKa for acetic acid is about 4.74. Therefore Acetic
acid/acetate buffer will work best at 4.74 +/- 1 pH unit and so the pH 8 is far
removed from that. Hence it would not buffer at that pH at all.</span>