accumulations of genetic mutations over time.
Genetic and epigenetic changes compound over time to cause cancer. While aging and chronic inflammation are the major causes of epigenetic changes, carcinogenic substances, UV radiation, and other conditions can also cause genetic changes. Our prior exposure levels and life history are reflected in the accumulation and patterns of changes in normal cells. The majority of accumulated changes are regarded as passengers, although they are linked to cancer drivers as they accumulate. Although only hypothesized for genetic changes, this has been demonstrated for aberrant DNA methylation. However, modern technology has made it possible to assess uncommon point mutations, and research has revealed that the rates of their accumulation do actually correspond with cancer risk.
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Answer:
Mechanisms are activated where it is sought to lower the amount of free protons in the blood, that is, to reduce acidity, these mechanisms work between two large systems, the receptor system, the respiratory system and the renal system.
Explanation:
When a metabolic acidosis is entered, either by a food, or by a disease or even an intense physical activity, the lungs seek to generate hyperventilation, to increase the concentrations of oxygen in plasma and absolutely decrease the carbon dioxide concentration, thus not the blood becomes even more acidic.
On the other hand, the digestive system together with the sensory system, will warn this proprioception of the acidity of the plasma and will promote the dilution of these acids with a solvent, which is water, promoting the sensation of thirst.
Finally, the kidneys will seek to retain all the alkaline solutes to neutralize the physiological internal pH, and will release through the urine and the channels of acidic compounds, the products or acid metabolites to the external environment, that is, acid urine excretion.
Answer:
Prokaryotic cells are much smaller than eukaryotic cells, have no nucleus, and lack organelles. All prokaryotic cells are encased by a cell wall. Many also have a capsule or slime layer made of polysaccharide. Prokaryotes often have appendages (protrusions) on their surface.
Answer:
The TATA box is an alternating sequence of Adenine and Guanine nucleotides that transcription factors bind to. The TATA box is found just before a gene. The transcription factors tell the RNA polymerase where to bind to begin transcription. This ensures the RNA polymerase will know where to start and which gene to transcribe.
Explanation:
