Answer and Explanation:
Ergotamine has been used for over 50 years and was the first specific drug to treat migraine attacks. Its therapeutic effect is due in part to its ability to contract the vessels. It is a vasoconstricting alkaloid used in migraine attacks, when treatment with non-steroidal anti-inflammatory drugs has no effect.
The mechanism of action of ergotamine is complex. The molecule has structural similarities to neurotransmitters such as seratonin, dopamine and adrenaline, and can therefore bind to various receptors and function as an inhibitor. Its use in the treatment of migraines is due to its vasoconstrictor effect of extracerebral intracranial blood vessels through their binding to the 5-HT1B receptor and inhibition of neurotransmitter binding.
Overuse of ergotamine may cause nausea, vomiting (to direct effects on the Central Nervous System in the vomiting centers) , malaise, headache, constriction of peripheral vessels and more severe effects such as ischemia of the extremities.
Ergotamine poisoning is called ergotism.
Ergotamine should not be used in patients with peripheral arterial or venous vascular insufficiency, ischemic heart disease, cerebrovascular disease, systemic infection and hypertension without effective control.
Which of the following statements is false? fas is characterized by brain damage, facial deformities, and growth deficits. the effects of fas are all reversible. heart, liver, and kidney defects are common, as are vision and hearing problems. individuals with fas have difficulties with learning, attention, memory, and problem solving.
b.) The efffects of FAS are all reversible.
Answer:
1. Biopsy: doctors take out tissue for testing at labs
2. Physical exam: doctors check your lips & mouth to look for anything that shouldn't be there (like sores or white patches)
Explanation:
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Watery eyes are a defense mechanism to foreign objects in the eye. The water will flush out the object.
