Well silly we would all be dead if it wasnt bonded right
Since the liver is the primary organ for metabolism, then in the setting of liver injury there will be reduced metabolism of compounds such as hormones. If these hormones are not metabolized and degraded in the liver, then these hormone levels will increase.
<em>A particular example is that the hormone estrogen is increased in the setting of liver damage, causing males with liver failure to have feminine characteristics.</em>
The stability of atoms depends on whether or not their outer-most shell is filled with electrons. If the outer shell is filled, the atom is stable. Atoms with unfilled outer shells are unstable, and will usually form chemical bonds with other atoms to achieve stability.