The most appropriate would be D or A. I don't see how wearing different shoes would help the clients knees.
Answer: coenzymes
Explanation:
These are non-protein organic materials which binds with enzymes to catalyze a reaction. They can as well be referred to as a co factor, the reason been that the assist the activity of enzymes. Examples of coenzyme are vitamin B and S-adenosyl methionine. It is also very important to know that coenzymes cannot function alone.
I believe I did this one before and I believe I put A and got it right