Answer:
Epinephrine binds to receptors on some smooth muscles (ex: around arterioles) → Ca++ released from ER → intracellular Ca++ up → stimulates contraction. c. Epinephrine binds to receptors on some smooth muscles (ex: around bronchioles) → phosphorylates protein needed for response to Ca++, preventing response.
In chromatin, substitution mutations are most common in linker regions. Option d is the correct answer.
Mutation by substitution When one nucleotide base is replaced by another, this occurs. Mismatch mutation A type of substitution mutation in which a single nucleotide is replaced, resulting in the coding of an incorrect amino acid, which usually results in a malfunctioning protein. Silent mutations are the result of genetic code redundancy (degeneracy): This is false, as silent mutations are the result of a base substitution that has no discernible effect on a protein's amino acid sequence.
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B1 (Thiamine), because chronic alcoholics often have poor nutrition, and Thiamine deficiency in the brain can lead to "Wernicke Encephalopathy."