The Roman empire reached its peak under the leadership of Trajan in 116 A.D
the empire endured great prosperity during the Pax Romana.
The correct answer to this open question is the following.
Although there are no options attached we can say the following.
One global process or series of events in the period 1450–1750 CE that would facilitate cross-cultural exchange could be the Columbian Exchange of those years.
Cristopher Columbus discovered America on October 12, 1492, when he and his sailors arrived at the islands in the Caribbean. Spanish King Ferdinand de Aragon and Queen Isabella de Castille had sponsored the trip of Columbus because they wanted to explore new routes to the Indies and get more richness for the Spanish Kingdom. Columbus' sailors were ambitious and also wanted a piece of the pie and aspire to get some precious metals such as gold, as part of the adventure.
After the discovery of the Americas and the conquest of the most important Mesoamerican civilizations, South American civilizations, and the founding of the North American colonies such as Jamestown, Virginia, the Columbian exchange was the series of trade and exchanges between America and Europe.
Through the Columbian Exchange, nations and their colonies traded raw materials, natural resources, goods, people, culture, and diseases.
Contrary to the previous answer to this question, Roman culture very much lived on.As the Western Roman Empire neared its end the Barbarians became "Romanized" in a sense much more than the Romans became "barbarized".
War, the systems and national bank