Question

select the correct answer sickle cells  disease is a hereditary mutation that causes The red blood cells to the form decreasing their ability to carry oxygen based on the image what kind of mutation occurs to cause Sickel cell disease

Answer 1

Answer:

Sickle cell disease is due to a type of substitution mutation.

Explanation:

Sickle cell disease is a condition that is transmitted from parents to children in an autosomal recessive inheritance pattern. It is due to a mutation that is capable of altering the shape of the erythrocyte, as well as its ability to circulate and carry oxygen.

The mutation that occurs in sickle cell disease is due to an alteration in the β-chain of hemoglobin, caused by the substitution of thymine base by adenine in the DNA that determines it. As a result, valine replaces glutamic acid in the β-chain amino acid sequence, with the consequences described.

• The other options are not correct because deletion, duplication and translocation correspond to chromosomal mutations, not responsible for sickle cell disease.