To begin with attempt to check whether there are any relatives I can contact, to illuminate them of the circumstance, and dangers of not transfusing, and talk about if these are genuinely the little girls wishes, and on the off chance that she comprehended that not accepting a transfusion could conceivably mean passing, and on the off chance that she was of sound personality when she settled on this choice. in the event that so then I would regard the desires and religious convictions of the patient and not transfuse, paying little respect to how troublesome, or my own perspectives.
Answer:
4 × 10^0 kg or 4×E0 kg.
Explanation:
Before delving into or solving the Calculation, let us check one or two things about worker bees.
WHAT IS A WORKER BEE?.
Bees generally are social insects living in an organized community and they consist of three castes which include; the drone bees, worker bees, and the queen bees.
The queen bees are the female bees while the drone bees are the male bees.
The WORKER BEES are female bees too, but the only difference between them and the queen bees is that they (worker bees) do not reproduce like the queen bees. They are saddled with the responsibility of looking for food and maintaining the hive temperature.
Now to the question, the mass of a bee= 1 × 10^-4 kg. And there are 4 × 10^4 bees in hive. Therefore, the mass of all the worker bees in the hive together = (1 × 10^-4) × (4×10^4).
==> 4 × 10^0 kg, or 4E0 kg.
Answer:
The correct insulin pathway is described as under:
2. Binding of insulin to the alpha subunit of the insulin receptor
8. Activation of insulin receptor tyrosine kinase
3. Phosphorylation of IRS proteins
6. Phosphorylation of phosphinositide 3-kinase (PI-3K)
4. Conversion of PIP2 to PIP3
7. Activation of PIP3-dependent protein kinase B (PDK1)
5. Glut4 receptors transported to the cell membrane
Explanation:
The insulin signaling pathway is described as under:
RTK (receptor tyrosine kinases) which is a receptor for insulin is an extracellular receptor but in contrast to other cell surface receptors it is catalytic in nature. In the absence of insulin (ligand), it is monomeric but as soon as it gets activated (activation occurs upon ligand binding), it undergo dimerization. It leads to auto-phosphorylation in it's tyrosine residue which subsequently leads to phosphorylation of tyrosine residue of other receptors. Such hyper-phosphorylated receptor have high affinity with enzyme/molecule like IRS protein which have SH2 domain . IRS down stream activates phosphinositide 3-kinase (PI-3K). This enzyme converts component of animal cell membrane PIP2 into PIP3. PIP3 also remains membrane bound but it has the potential to phosphorylate another enzyme named as PIP3-dependent protein kinase B (PDK1). Further, PDK1 leads to the activation of Akt or PK-B. Akt is a serine-threonine kinase which ultimately leads to the recruitment of Glut4 receptors on cell membrane for uptake of more and more glucose into the cell.
Note: Apart from this Akt also phosphorylates another protein named as FOXO which ultimately causes cell growth, Akt can also phosphorylate BAD protein so as to restrict cell apoptosis or we can say it leads to cell survival, Akt also leads to translation in a cell with the help of mTOR raptor etc.
Haploid refers to a cell that has has only one copy of each chromosome, like in a gamete such as a sperm cell or egg cell. Upon fertilization, the two haploids come together to form a full diploid cell (two copies of each chromosome) which then goes on to form the complete organism. Monosomy refers to a condition where there is only one copy of a specific chromosome. For example, in the human condition Turner Syndrome, there is only one X chromosome, instead of two sex chromosomes. Most incidences of monosomy other than Turner Syndrome are lethal, so there aren't many examples of it.