<h3><u>Answer;</u></h3>
b). Activation of an upstream guanine nucleotide exchange factor
<h3><u>Explanation</u>;</h3>
- <em><u>When a ligand activates the G protein-coupled receptor, it induces a conformational change in the receptor that allows the receptor to function as a guanine nucleotide exchange factor (GEF) that exchanges GDP for GTPthus turning the G protein-coupled receptor on.</u></em>
- The activated G-protein then dissociates into an alpha (G-alpha) and a beta-gamma complex.
It is called haemogloblin.
Answer: A PEDIGREE is a family-tree like representation of how organisms are related based on ANCESTRY. It shows genetic relatedness or blood relationship between individuals or organisms.
Explanation: Pedigree can be used to determine
1. Family history or genealogy.
2. Genetic or blood relationship.
3. Coefficient of relationship.
4. Degree of relationship.
5. Proportions of shared genes.
6. Mode of transmission of diseases.
7. Risk evaluation or determination.
Genetic counseling.
8. Linkage analysis.
Pedigree symbols are used in constructing pedigree.