Rough endoplasmic reticulum contains ribosomes, while smooth endoplasmic reticulum does not contain ribosomes. The ribosomes are what give rough endoplasmic reticulum its characteristic "roughness."
I'm guessing Liver.
If it was in the stomach, we wouldn't get belly aches. If it were in the large intestine, we wouldn't poop. So that's my guess.
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The answer is tissue fluid. Tissue fluid holds far smaller quantity of protein molecules because they are too large to escape easily over the tiny holes in the capillary endothelium. Tissue fluid doesn't contain red blood cells because they are too large, but does comprise some white blood cells.