A population consists of all the organisms of a given species that live in a particular area
Which statement about somatic mutations is true? They exist in all the cells of the body
Answer:
Repair mechanism for base cleavage (BER)
Explanation:
Repair by base cleavage (BER)
The altered bases are specifically recognized by glycosylases and removed, generating an AP site. The hole is filled by a DNA polymerase that takes the healthy strand as a template. This system arises not only by exposure to external agents, but also by the cell's own activity.
In case of damage in more than one nucleotide, repair by nucleotide excision (NER) is performed.
Nucleotide excision repair (NER)
The damaged area is recognized by UvrA and B, then A and B separate and UvrC enters which forms a complex with endonuclease activity with B. This enzyme cuts the T-dimer and the gap is filled by a DNA polymerase. There is also the TC-NER system (transcription-coupled nucleotide repair system). The alteration of these mechanisms gives rise to diseases such as: Xeroderma pigmentosum, Trichotiodystrophy or Cockayne Syndrome
