Why is a single base-pair deletion mutation within a protein-coding sequence more likely to be harmful than a single base-pair c

Question

Mkey [24]

3 years ago

13

Why is a single base-pair deletion mutation within a protein-coding sequence more likely to be harmful than a single base-pair c

hange mutation?

Biology

1 answer:

Serggg [28] · Answer 1 · 2022-02-08T10:17:36+03:00

Serggg [28]3 years ago

7 0

A single base-pair deletion would cause a frameshift mutation, disrupting every codon sequence read after it. A single base-pair change, however, only affects one codon. It is therefore less likely to cause harm.