The correct answer is: 2- Hypertension, or high blood pressure
Hypertension leads to heart failure. Also, as a result of hypertension body tends to retain fluid in order to maintain adequate blood volume. A failing heart is unable to handle that extra fluid, so it is transferred out of the blood vessels and into tissues causing the swelling of extremitets or edema.  
 
        
             
        
        
        
The homologous chromosomes separate during second division
        
             
        
        
        
Hydrophilic and hydrophobic