The mechanism of action of Bordetella pertussis is to stop the cilia of epithelial cells from beating.
<em>Bordetella pertussis</em> is a pathogenic, gram-negative bacteria. It is the causative agent of highly communicable respiratory disease known as pertussis or whooping cough.
The mechanism of action of Bordetella pertussis:
- This bacterium colonizes the ciliated epithelial cells of the respiratory airways of the host.
- A surface protein on the bacteria called filamentous haemagglutinin adhesin binds to sulfatides on the cilia of epithelial cells. When the bacterium is anchored, it releases tracheal cytotoxin, which prevents the cilia from beating.
- As a result, the cilia in an organism's lungs are unable to sweep out foreign material, and the body reacts by causing the host to cough. When people cough, bacteria are released into the air, where they might spread to other hosts.
- Another toxin called the pertussis toxin, often known as PTx, prevents adenylate cyclase from using ATP to convert to cyclic AMP. This results in over-conversion of ATP to cyclic AMP, which may interfere with cellular signaling systems. As a result, phagocytes are unable to respond to an infection effectively.
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Answer:
Verify if the aunt has the right to consent for the child, then proceed.
Explanation:
It is very important to know if the aunt has the consent of the child's parents to make a medical decision. This is because the child is a minor and cannot make a decision about whether or not to accept the procedure. Then a responsible adult of the child must sign documents that make clear the knowledge of the implications of the procedure.
"Bottleneck effect" is the evolutionary mechanism among the choices given in the question that this effect. The correct option among all the options that are given in the question is the second option or option "B". I hope that this is the answer that you were looking for and it has come to your great help.
