3 years ago

What enzyme catalyses the reaction of PRPP transfer to hypoxanthine with formation of IMP?

Chemistry

1 answer:

Alona [7]3 years ago

8 0

Answer:

HPRT

Explanation:

HPRT catalyzes the salvage reactions of hypoxanthine and guanine with PRPP to form IMP and GMP

The formation of GMP from IMP requires oxidation at C-2 of the purine ring, followed by a glutamine-dependent amidotransferase reaction that replaces the oxygen on C-2 with an amino group to yield 2-amino,6-oxy purine nucleoside monophosphate, or as this compound is commonly known, guanosine monophosphate.

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