D or aka changes in the moons orbit
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Answer:
Use the rule that 10% of the energy is transferred between layers.
Explanation:
Energy is transferred between layers of a food pyramid. That means that the producers at the bottom of the pyramid (e.g. green plants) provide energy to the primary consumers (e.g. rabbits), which are eaten by and provide energy to the secondary consumers (e.g. foxes).
However, very little of the energy is actually transferred to the next layer, roughly 10%. So an easy way to calculate the energy available at each level is to calculate 10% of what was available from the previous level. So if there is 600 kJ available from the primary consumers, then 60 kJ are transferred to the secondary consumers
Protein-protein interactions within the CARMA1-BCL10-MALT1 complex:
- The T-cell receptor and B-cell receptor-dependent NF-B induction and lymphocyte activation are mediated by the CBM complex, which is made up of the proteins CARMA1, BCL10, and MALT1.
- Each of the proto-oncoproteins CARMA1, BCL10, and MALT1 is a somatic gain-of-function mutation or chromosomal translocation, and dysregulation of CBM signaling is a characteristic of numerous lymphoid malignancies, including Activated B-cell Diffuse Large B-cell Lymphoma.
- Moreover, a number of immunological dysregulation diseases have been linked to both gain- and loss-of-function germline mutations in CBM complex proteins.
- Over the past ten years, careful examination of the interactions of CBM components has yielded a wealth of detailed structural knowledge.
- Here, we discuss important discoveries about the molecular nature of these protein-protein interactions that have helped the research develop a detailed understanding of how these proteins come together to form high-order filamentous CBM complexes.
- Approaches to therapeutic suppression of the CBM complex have thus far centered on obstructing MALT1 protease activity in order to treat lymphoid malignancy and/or autoimmunity.
- The structural effects of MALT1 protease inhibitors on significant protein-protein interactions are also reviewed in detail.
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