Answer:
a) There are lots of genes on chromosome 1 could be affected, and the gametes could be imbalanced (missing segments of DNA or whole chromosomes)
b) Roughly 50%
c) No. I would advise that the couple undergo preimplantation genetic diagnosis, so that a zygote carrying the normal copy of chromosome 1 could be selected.
Explanation:
Chromosome 1 is one of the largest and most gene rich chromosomes. An inversion that covers 70% of its length would cover lots of genes.
While an inversion on its own would not seem problematic (as all the genes on the chromosome are still there), when it comes to meiosis, the sister chromatids would not be able to correctly align, and crossing over would further complicate this. It could also lead to unbalanced gametes missing entire parts of the chromosome. Therefore, there are likely numerous genes that will be affected and messed up by the inversion.
This could explain the high incidence of past still births, as if lots of genes are affected, and non-functional, the pregnancy would be rendered non-viable, or highly deleterious causing premature death.
b) There is a 50% chance of a child inheriting the defective copy of chromosome 1 (and 50% of a chance of them inheriting the normal chromosome 1. Therefore, there is likely a 50% chance that future offspring would be affected by defects
c) No. I would advise that the couple undergo preimplantation genetic diagnosis. In this, the couple undergoes in vitro fertilization (IVF). When embryos are produced through IVF, they can then be tested for the presence of the abnormal chromosome. Embryos will only be implanted into the mother if the normal chromosome 1 is present.
The answer is <span>gametes:</span>
Phagocytes refer to the procedure by which some kind of living cells known as phagocytes engulfs or ingest other cells or particles. The phagocyte may be a free-living one-celled species, like an amoeba, or one of the body cells, like a white blood cell.
In higher species, phagocytosis is mainly a defensive mechanism against infection and invasion of the body by the antigens, that is, foreign particles.
Thus, phagocytosis is illustrated by most types of white blood cells ingesting bacteria, viruses, and other foreign substances.
