Aztec people of Mexico dying of smallpox introduced by the Spaniards. Epidemics soon became a common consequence of contact. In April 1520, Spanish forces landed in what is now Veracruz, Mexico, unwittingly bringing along an African slave infected with smallpox.
<span>When Lewis and Clark went on their expedition they talked to the natives about the government and attempted to make friends. They treated the natives well and gave them lots of gifts. They wanted to facilitate a good relationship and friendship.</span>
Anglo-American colonization in Mexican Texas took place between 1821 and 1835. Spain had first opened Texas to Anglo-Americans in 1820, less than one year before Mexico achieved its independence.