Answer:
two, phospholipids, non polar, tails, polar, heads.
Explanation:
This is just basically illustrating one of the components of the lipid bilayer memebrane. The membrane is made up of two lipid layers with the polar head groups facing either the cytosol or the outer surroundings while the non polar tails facing each other. Such that this bilayer act as a barrier between the cytosol of the cell/organelle eg endoplasmic reticulum and the outer surroundings.
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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arbon, as with many elements, can arrange its atoms into several different geometries, or "allotropes." In pure diamond, every carbon atom is covalently bonded to exactly 4 other carbon atoms in a very specific and energetically favorable geometry. The diamond cannot be broken or scratched unless many covalent bonds are broken, which is difficult to do. In another common allotrope, graphite, every carbon atom is covalently bonded to only 3 other carbon atoms, and the atoms are arranged in sheets that are not covalently bonded to each other. The sheets can be broken apart easily, ultimately meaning that graphite can be easily scratched. Coal is composed of particles of different allotropes of carbon, and some "amorphous carbon," which has no defined geometry in its atomic structure. Without a continuous network of covalent bonds, coal is easily scratched (i.e. it is not hard).
Hey there,
To be exact, <span>1,048,576 Kilobytes
Hope this helps :))</span><span>
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Answer: <em>C.) Cnidarians</em>
