<span>A drug used to treat CML, imatinib, binds to the active site of Abl kinase. Why does this drug work to treat this type of cancer?
</span><span>B) By binding to the active site, the drug prevents the ability of Abl kinase to bind to its substrate.
</span>
Imatinib works against CML by binding close to the ATP binding site of bcr-abl. The binding results to the<span> locking in of the bcr-abl to a closed or self-inhibited conformation and inhibiting the enzyme activity of the protein </span><span>semi-competitively.</span>
Storage. Vacuoles store water and waste.
Answer:
Answer
Explanation:
The wind and water can break down the landscape and affect its physical formation. Water for example can break down rocks and make a ditch from 1 foot deep to 6 feet deep.
<h3><u>Answer;</u></h3>
A. counterclockwise toward the center
<h3><u>Explanation;</u></h3>
- <em><u>In the Northern Hemisphere, winds associated with a low-pressure system blow in a counterclockwise direction towards the center, while those that are associated with a high-pressure system blow in clockwise direction outwards from the center.</u></em>
- In the Southern Hemisphere on the other hand, winds that are associated with a low-pressure system blow clockwise towards the center.
- <em><u>The rotation of the earth creates a force called the Coriolis force, which gives the wind that is within high pressure systems a clockwise circulation in the northern hemispheres and a counterclockwise circulation in the southern hemisphere.</u></em>
