I believe it is B i took this test last year.
Answer:
Option A, a drug to treat high blood pressure that reversibly inhibits an enzyme catalyzing production of a chemical that causes blood vessels to contract
Explanation:
The complete question is
If you were working for a pharmaceutical company as part of a drug discovery team, which of these enzyme inhibitors would you suggest as a productive avenue for drug development?
a) a drug to treat high blood pressure that reversibly inhibits an enzyme catalyzing production of a chemical that causes blood vessels to contract
b) a drug to treat diabetes that irreversibly inhibits an enzyme in the metabolic pathway to synthesize glucose
c) a compound that acts as a competitive inhibitor for a digestive enzyme produced only in the presence of certain foods
d) a compound that inhibits enzymes by significantly changing the ph throughout the body
Solution
Productive avenue of a drug simply means producing an drug that not only treats the main disease or disorder but also functions to inhibit the causative agent activity. In case of option A, both the objectives of producing drug are met and hence it is the right choice.
High blood pressure usually affects the blood vessels by narrowing them and in severe cases may rupture them. If a drug as stated in option A is produced, it will not only rectify the effects of high blood pressure but will also prevent the blood vessels from narrowing by inhibiting the activity of enzymes responsible for producing chemical that leads to blood vessel contraction.
Hence, option A is correct
The answers are; TRUE
Pressure increase towards earth’s interior because the further deeper you go the higher the rock layers above that apply pressure towards the center of the earth by gravity. In addition , due to this increasing pressure, temperatures also increase because the two parameters are directly proportional.
A mechanism that is effective in maintaining a normal glomerular blood pressure only if the systemic mean arterial pressure remains between 80 and 180 mm hg is called renal autoregulation.
<h3>What is renal autoregulation?</h3>
- Autoregulation is the inner characteristic of blood vessels present in end organs, like heart, kidney, and mind, by which they dilate or constrict in response to pressure changes, thus help to keep the blood flow generally steady.
- Usually our body tries to regulate our blood pressure in range of 50 to 150 mm Hg.
- Regulation of renal blood flow and glomerular blood pressure in kidneys is called renal autoregulation.
- There are 3 mechanisms of renal blood flow namely myogenic response (MR), tubuloglomerular feedback (TGF) and third mechanism that is independent of TGF but slower than MR.
Learn more about renal autoregulation here:
brainly.com/question/28064114
#SPJ4
