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Carbon dioxide is transported in the blood from the tissue to the lungs in three ways:1 (i) dissolved in solution; (ii) buffered with water as carbonic acid; (iii) bound to proteins, particularly haemoglobin. Approximately 75% of carbon dioxide is transport in the red blood cell and 25% in the plasma.
Amphibia is the class of vertebrates which is considered to be the first to develop lungs. This allowed amphibians to live successfully on land as terrestrial organisms. Ichthyostega was the first primitive amphibians with nostrils and lungs. Amphibians adopted themselves to live on land with developed lungs.
