The most deadly illness the pioneers have faced was Oregon Trail, it was spread by for hunting food, picking berries, and most of all this terrible game kids used to play that made them realize the Oregon Trail was real. It also lead up to bad fever, cholera, and dysentery.
This is the main reason of the deadly illness pioneers had.
Hope this helps you :)
The focus of the Renaissance at the time was on the works of
the Greeks and Romans. Emphasis was more
human activities like science, literature and the arts. This was called
Humanism where the focus of learning was on culture. Knowledge and ideas once lost was revived and
was now growing in Europe and this helped in cultural and intellectual
development.