. Aşağıdaki şekilde hazırlanan tampon çözeltilerin pH'larını hesaplayınız? a) 8 mmol NaCH3COO+ 200 mL 0.1 M CH3COOH b) 100 mL 0.
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Answer:
0.033
Explanation:
Tay–Sachs disease is an autosomal recessive disorder. The possible genotypes and phenotypes are:
- TT = normal
- Tt = carrier
- tt = Tay-Sachs disease
I will use <em>p </em>to call the frequency of the dominant <em>T</em> allele, and <em>q</em> the frequency of the recessive <em>t</em> allele.
If the population is in equilibrium, the frequency of the tt genotype is q².
The frequency of the Tt genotype is 2pq.
The Tay–Sachs carrier frequency will be 0.033