Cannabinoid receptors, located throughout the body, are part of the Endocannabinoid system which is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory.[1]
Cannabinoid receptors are of a class of cell membrane receptors under the G protein-coupled receptor superfamily. As is typical of G protein-coupled receptors, the cannabinoid receptors contain seven transmembrane spanning domains.[5] Cannabinoid receptors are activated by three major groups of ligands: endocannabinoids, produced by the mammillary body; plant cannabinoids (such as Cannabidiol, produced by the cannabis plant); and synthetic cannabinoids (such as HU-210). All of the endocannabinoids and plant cannabinoids are lipophilic, such as fat soluble compounds.
Energy cannot be destroyed
Answer:
Causal association is defined as two events in which one event leads to the cause/development of the second event such as the consumption of trans-fats and the onset of heart disease. In order to show the causal association, it is necessary to ensure that the 3 criteria of temporality, consistency, and strength are satisfied with respect to the relationship between consumption of trans fats and heart disease. According to this example involving the relationship between trans-fats and heart disease, temporality could be satisfied if one is consuming an excessive amount of foods containing trans-fats such asFrench fries, and who then ends up suffering from heart disease. In order to fulfill the criteria of strength, statistical tests would need to be performed in order to establish that there is a positive correlation between the individuals who consume trans-fats 10 times per week are shown to develop and require treatment for heart disease 90% of the time. Lastly, consistency may be fulfilled by showing that the same results are occurring despite applying the same testing measures on different groups of individuals during various increments. By applying the same tests on different groups, the chances of creating false-positives within the study can be significantly lowered. Numerous studies can be used to determine whether meaningful statements regarding the causal relationship between two factors can be established. By performing multiple studies on individuals’ eating habits and their health outcomes, researchers may then determine whether a relationship exists between the health challenges that they are faced with and the items that they consume.
Explanation:
Answer:
(a) 1/2; (b) no
Explanation:
Glucose-6-phosphate dehydrogenase deficiency (G6PD) is an X-linked recessive disorder and the woman's father was diseased so it means that woman is a carrier of the allele but has normal phenotype. It means that she will have XXᵇ genotype.
In contrast to this, her husband is diseased so his genotype will be XᵇY.
The Punnett square diagram related to the cross is attached.
(a) Proportion of their sons expected to be G6PD is 1/2:
They both may give birth to 4 progeny with genotypes XXᵇ, XᵇXᵇ, XY and XᵇY. It means they both may have 2 sons out of which one with genotype XᵇY will be diseased while the one with genotype XY will be healthy. So the proportion of their sons having G6PD is 1/2 or 50%.
(b) If the husband were G6PD deficient, the answer will not change.
The reason behind this is that this disease is caused by an allele located in X chromosome. But father contributes only Y chromosome to his son not X chromosome. The X chromosome will affect the genotype of his daughter not son that is why answer will not change. It means they will still have 1/2 of their sons diseased.
