The type of drug you're looking at is a wide classification of drug called either a depressant or an "downer". Opiates, alcohol, and benbenzodiazipenall make up this drug classification.
Answer: Coronary Artery disease
Explanation:
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This can change the hormones in women and cause mood changes which can be drastic including things like depression, stress, and anxiety. It has not been known to cause PMS but has been know to make it worse.