1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Temka [501]
3 years ago
8

Two protein kinases, PK1 and PK2, work sequentially in an intracellular signaling pathway.You create cells that contain inactiva

ting mutations in the genes that encode either PK1 or PK2 and find that these cells no longer respond to a particular extracellular signal.You also create cells containing a version of PK1 that is permanently active and find that the cells behave as though they are receiving the signal even when the signal is not present.When you introduce the permanently active version of PK1 into cells that have an inactivating mutation in PK2, you find that these cells also behave as though they are receiving the signal even when no signal is present.
A.From these results, does PK1 activate PK2, or does PK2 activate PK1? Explain your answer.
B.You now create a permanently active version of PK2 and find that cells containing this version behave as though they are receiving the signal even when the signal is not present.What do you predict will happen if you introduce the permanently active version of PK2 into cells that have an inactivating mutation in PK1?
Biology
1 answer:
nikitadnepr [17]3 years ago
8 0

Answer:

a. PK2 activates PK1

b. no response would be produced

Explanation:

Kinases are enzymes known to phosphorylate different substrates, thereby activating/inactivating them. In this case, a mutation that produces a constitutively (permanently) active PK1 kinase is itself able to continue the signaling pathway, independently of whether or not PK2 is present. This constitutive mutation shows that PK1 is recruited to continue signaling events within the cell and, therefore, PK1 activation is downstream in the signaling pathway. Conversely, cells containing active PK2 and inactive PK1 would be unable to continue the signaling pathway since PK2 activation is upstream of the induction of PK1, and thereby these cells cannot respond to the signal (PK2 activation).

You might be interested in
Is throwing a curve ball an example of potential or kinetic energy?
shutvik [7]
Throwing a ball is an example of kinetic energy. I do not have any proof or any reasons, but for now I just know that it's kinetic energy. You can also look it up and you'll see the answer automatically. Hope this helps :) If you want any proof, please feel free to ask me thru contact :)
3 0
3 years ago
What is bitumen? a type of clay a handle for a knife an engraved plaque a tar-like substance?
LenKa [72]
It is a tar like substance
7 0
3 years ago
What is one piece of evidence that some organelles like mitochondria and chloroplasts within eukaryotes used to be independent p
Svet_ta [14]

Answer:

organelles are very similar to present-day bacteria, suggesting a common ancestor.

Explanation:

Some evidence suggests that some organelles like mitochondria and chloroplasts within eukaryotes were once used to be independent eukaryotes.

Endosymbiosis theory says that ancestral prokaryotic cells engulfed bacteria like cyanobacteria which with time evolved into mitochondria and chloroplast. Molecular evidence also proves that these organelles were once prokaryotic organisms because they show similar genetic makeup and ribosome type.

So these organelles are similar to present-day bacteria showing that they have a common ancestor.

6 0
3 years ago
Which of the following statements represent evidence supporting the endosymbiotic theory? Check all that apply.
Tems11 [23]

Answer:

The statement that says " The mitochondrion contains a circular chromosome that has bacterial DNA sequences" is true among the all statement given above.  

Explanation:

The Endosymbiotic theory that is other wise known as the symbiogensis illustrates the occurrence of the eukaryotic cell from the prokaryotic cells. Mitochondria and plastids are the most studied example in support of this theory. This theory explains that the aforementioned organelles are formed as they are taken inside in one another by the prokaryotic cell. Some of the evidences in support of this theory are mentioned below:

  • Phylogenetic similarity between the mitochondria and chloroplast to the proteobacteria and cynobacteria respectively.  
  • Ability of these organelles to divide only through binary fission as the bacterial population.
  • The associated ribosomes are similar to the bacterial ribosomes.  
  • Presence of porins in these organelles similar the bacterial membrane.  

5 0
3 years ago
Which of the following statements describes solar prominences?
Sonja [21]

Answer: A

Explanation:

5 0
3 years ago
Read 2 more answers
Other questions:
  • Neither _____ nor _____ are included on the Social Readjustment Rating Scale.
    5·1 answer
  • The __________ bone is located just below the urinary bladder.
    14·1 answer
  • Fungi cannot make their own food through photosynthesis. How do they take in nutrients ? A.Absorbing sunlight B.producing spores
    12·2 answers
  • which structure in plants produce a substance that protects the extending roots from developing friction?
    15·2 answers
  • Specialized vacuole that pinches off golgi and delivers macromolecules
    8·1 answer
  • At what point in the eukaryotic cell cycle does mitosis occur
    7·1 answer
  • 3. An irregularly shaped stone was lowered into a graduated cylinder
    13·1 answer
  • List the four eras on the geologic time scale describe one identifying type of organism from each era
    10·2 answers
  • Which is one place that glaciers are found?
    12·2 answers
  • On the wave diagram pictured below, what is the term for points B and F?
    6·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!