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The Second World War (WWII) was one of the major transformative events of the 20th century, with 39 million deaths in Europe alone.
Periods of hunger became more common even in relatively prosperous Western Europe.
Putting aside the very real human cost, war has also serious economic costs – loss of buildings, infrastructure, a decline in the working population, uncertainty, rise in debt and disruption to normal economic activity.
If wars alter long-term economic growth, they would permanently depress economic prospects of future generations so they had to surrender.
Mortality rate has reduced, lack of father to children and the war has cause severe hungers
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In a way, this is a double edged sword. On one hand, the animals are needed to best test the effects, but on the other hand it can be seen as very unethical. Honestly, I don't really see a way around using the animals. Unless you get human volunteers, but there is no way to fully make them understand what they are getting themselves into which can turn unethical very, very fast. If all of a sudden one of your human volunteers decides that they do not want to be a part of the test anymore, there is noting you can do to reverse what has already been done.