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Drug-drug interactions (DDIs) are one of the commonest causes of medication error in developed countries, particularly in the elderly due to poly-therapy, with a prevalence of 20-40%. In particular, poly-therapy increases the complexity of therapeutic management and thereby the risk of clinically important DDIs, which can both induce the development of adverse drug reactions or reduce the clinical efficacy. DDIs can be classify into two main groups: pharmacokinetic and pharmacodynamic. In this review, using Medline, PubMed, Embase, Cochrane library and Reference lists we searched articles published until June 30 2012, and we described the mechanism of pharmacokinetic DDIs focusing the interest on their clinical implications.
Keywords: Absorption, adverse drug reaction, distribution, drug-drug interactions, excretion, metabolism, poly-therapy
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Answer: B, health and safety. Hopefully that helps!
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Protect them from injury by helping them to the floor and clearing away furniture or other items. Do not put anything in their mouth as it could lead to injury. Do not try to stop their movements. You may remove eyeglasses or other items that could cause injury. Time the seizure, call 9-1-1 if it lasts longer than 5 minutes. Reassure them and try to help them stay calm . Gently help them roll onto their side and push the angle of the jaw forward to assist with breathing, this is the recovery position
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