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Law Incorporation [45]
3 years ago
14

Which physical property is the rate at which

Biology
1 answer:
Damm [24]3 years ago
6 0
I is answer. Don't open link. It is most likeky unsafe.
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Place all eight of these steps of the insulin signaling pathway in the correct order. The abbreviation PIP 2 is used for phospha
DedPeter [7]

Answer:

The correct insulin pathway is described as under:

2. Binding of insulin to the alpha subunit of the insulin receptor

8. Activation of insulin receptor tyrosine kinase

3. Phosphorylation of IRS proteins

6. Phosphorylation of phosphinositide 3-kinase (PI-3K)

4. Conversion of PIP2 to PIP3

7. Activation of PIP3-dependent protein kinase B (PDK1)

5. Glut4 receptors transported to the cell membrane

Explanation:

The insulin signaling pathway is described as under:

RTK (receptor tyrosine kinases) which is a receptor for insulin is an extracellular receptor but in contrast to other cell surface receptors it is catalytic in nature. In the absence of insulin (ligand), it is monomeric but as soon as it gets activated (activation occurs upon ligand binding), it undergo dimerization. It leads to auto-phosphorylation in it's tyrosine residue which subsequently leads to phosphorylation of tyrosine residue of other receptors. Such hyper-phosphorylated receptor have high affinity with enzyme/molecule like IRS protein which have SH2 domain . IRS down stream activates phosphinositide 3-kinase (PI-3K). This enzyme converts component of animal cell membrane PIP2 into PIP3. PIP3 also remains membrane bound but it has the potential to phosphorylate another enzyme named as PIP3-dependent protein kinase B (PDK1). Further, PDK1 leads to the activation of Akt or PK-B. Akt is a serine-threonine kinase which ultimately leads to the recruitment of Glut4 receptors on cell membrane for uptake of more and more glucose into the cell.

Note: Apart from this Akt also phosphorylates another protein named as FOXO which ultimately causes cell growth, Akt can also phosphorylate BAD protein so as to restrict cell apoptosis or we can say it leads to cell survival, Akt also leads to translation in a cell with the help of mTOR raptor etc.  

5 0
3 years ago
Fill in the blanks pls n ty i will kiss u. !4?2!4$
Pani-rosa [81]
In order: 50% 0% 100%? 50%
you have a 50% chance of having healthy offspring b/c they do not possess the gene
0% b/c they all carry the disease
100% b/c all of them have the recessive gene
50% b/c there’s only two that are completely recessive (aa)
6 0
3 years ago
I’ll mark brainliest <br> how do organisms with many cell types develop from a single cell
Rashid [163]

Answer:

A multicellular organism develops from a single cell (the zygote) into a collection of many different cell types, organized into tissues and organs.During development, cells use both intrinsic, or inherited, information and extrinsic signals from neighbors to "decide on" their behavior and identity.

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3 years ago
What process is happening in the diagram?
Sveta_85 [38]

Answer:

B

Explanation:

5 0
3 years ago
Read 2 more answers
Bands in metamorphic rocks are formed by A.different chemicals in the earth coloring the rock B.the layering of the rock C.the m
sattari [20]

B. The layering of the rock.

Happy to help. Please mark as brainliest!

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3 years ago
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