Answer:
the pathway will be under-expressed.
- the alpha subunit helps to bind with either GDP or GTP. when the α subunit is bound with GDP, it will be bound to β and γ subunits and thus forms an inactive state for G-protein.
- when the alpha subunit binds with the GTP, it becomes activated and dissociates β and γ subunits.
if G-protein Coupled Receptor is unable from dissociating β and γ subunits, then the pathway will go under expression.
The chemical qualities of the alpha subunit allow it to bind easily to one of two guanine subunits, GDP or GTP. The protein thus has two functional formations. When GDP is bound to the alpha subunit, the alpha subunit remains bound to the beta-gamma subunit to form an inactive trimeric protein.
G-proteins, cAMP, and Ion Channel Opening. The alpha subunit activates adenylate cyclase, in purple, and loses GTP. Adenylate cyclase converts ATP to cyclic AMP, which then activates Protein Kinase, shown in blue. Protein Kinase phosphorylates an ion channel, letting sodium ions rush into the cell.
As a result of the ligand binding to its site on the G-protein-linked receptor, A) the G-protein changes conformation and GTP replaces the GDP on the alpha subunit. ... Inactivation of the alpha subunit occurs when its own phosphorylase activity removes a phosphate from the GTP.
The answer is A, because some diseases are genetic, and Shannon could be at risk of an underlying disease.
A nucleotide consists of three things: A nitrogenous base, which can be either adenine, guanine, cytosine, or thymine (in the case of RNA, thymine is replaced by uracil). A five-carbon sugar, called deoxyribose because it is lacking an oxygen group on one of its carbons. One or more phosphate groups.
I think the correct answer from the choices listed above is the third option. The barrel of a gun is also known as bore. The barrel is the metal tube which the bullet is fired and the bore is the inside of the barrel. It is the one closest to the barrel so it must be the answer.
Answer:
The correct answer is d) genomic imprinting.
Explanation:
Genomic imprinting is a biological process by which specific modifications in the germ line that produce differences in the expression of the genetic material that is biochemically marked indicating its parental origin. The Prader-Willi syndrome is one of the best known and most studied examples in relation to pathologies produced by genomic imprinting. Prader-Willi syndrome is a complex genetic disease that is fundamentally neurological. Its appearance is due to a deletion of a fragment of chromosome 15 derived from the father.
