It would be completely false to say that both internal and external environments can modify or alter a gene. The correct option among the two options that are given in the question is the second option or the last option. I hope that this answer has come to your great help.
The endoplasmic reticulum serves many general functions, including the folding of protein molecules in sacs called cisternae and the transport of synthesized proteins in vesicles to the Golgi apparatus.
Gg and Rr hope this helps:)
