B. usually contains a large amount of matrix
Answer:
DNA vaccines consist of DNA vectors or plasmids (small double-stranded DNA rings originally derived from bacteria, but unable to cause infection) into which the genes encoding one or more immunizing proteins of the infectious agent have been inserted causing the disease to be prevented.
Explanation:
Vectors are the functional unit of naked DNA vaccines. Genes that encode the proteins of interest and are of bacterial origin are inserted into these vectors. Bacterial plasmids are circular DNA molecules that self-replicate extrachromosomally in bacteria. The genes encoded in these plasmids are under the control of promoters, almost always of viral origin. When a plasmid is introduced into the cell it translocates to the nucleus, where transcription of the transgene begins; the transcripts are then taken to the cytoplasm and translated there. The newly synthesized proteins are degraded in the proteasome to 8-10 amino acid peptides, which are transported to the endoplasmic reticulum. Peptides of high affinity with their respective MHC I molecule stabilize and enter the secretory pathway, thus reaching the cell surface, where they are coupled with the T-lymphocyte receptor (TcR) present on the surface of T lymphocytes cytotoxic drugs (CD8 +) to induce their activation.
Answer:
There are many questions that can be answered by science but I will provide some examples below.
Explanation:
Science involves many areas of study, <u>from biology and chemistry to physics and neuroscience</u>. Generating questions and providing answers are the most important steps in science as this process has allowed thousands of scientists to develop new drugs to treat previously-mortal diseases, to protect endangered species, to prevent population declines, to understand the behavior of fauna, among many other remarkable outcomes and discoveries.
In this answer, I will focus on some questions belonging to the life sciences areas that can be answered by science:
Biology
<em>How does climatic phenomena, such as El Niño and La Niña, affect the migration of whales?</em>
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Neuroscience (humans)
<em>Is schizophrenia hereditable?</em>
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Behavioral Ecology
<em>Does climate change affect the capability of cuttlefish to camouflage?</em>
Neuroscience (Animals)
<em>Are killer whales capable of problem-solving?</em>
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Ecology
<em>How does the reduction of apex predator populations (terciary consumers) affect the population of secondary consumers?</em>
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Conservation Biology
<em>Why do increased temperatures lead to coral bleaching? What is the mechanism and how can it be controlled?</em>
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Animal Behavior
<em>What is the mechanism that Ophiocordyceps unilateralis (Zombie fungus) uses to manipulate ants for its own disperal?</em>
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Parasitology
<em>Does the parasite Toxoplasma gondii induce erratic behaviors in humans?</em>
Answer:
Jean-Baptiste Lamarck
Explanation:
Jean-Baptiste Lamarck was a French biologist which developed the first theory to understand how species change (evolve) over time. This evolutionary concept was published under the name of 'Theory of the Transmutation of Species' in the early 19th century. Subsequently, Darwin published his famous and widely accepted evolutionary theory in the book 'On the Origin of Species' (1859).
C eastern Europe
Mostly near the baltics and the Balkans, but Czech is also a slavic language.
