I believe the correct answer would be metabolism. This comprises all of the reactions inside organisms that allows them to sustain life. There are two categories of such namely, anabolism and catabolism. Hope this answers the question.
DNA replication needs to occur because existing cells divide to produce new cells. Each cell needs a full instruction manual to operate properly. So the DNA needs to be copied before cell division so that each new cell receives a full set of instructions!
One explanation could be the differences in climate (environmental factors). The climate in northern Mexico could support the reproduction of the mosquito species, which is a vector of the dengue virus. Other environmental conditions that influence its endemicity could include living conditions and sanitation. The other possiblity could be that the people in the US have developed immunity for the disease, therefore, are unaffected even when infected by the virus.
A river delta
Hope it helped!