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tia_tia [17]
3 years ago
14

Anthony Hoffnagle was well until after 6 months of age when he was hospitalized for pneumonia 5 times in the same year. A consul

tation with an immunologist revealed normal numbers of B cells and T cells, slightly elevated IgM, and a marked decrease in IgG and IgA. He was diagnosed with X-linked hyper IgM syndrome. Based upon the information in the previous questions, what is the most important gene that might be defective that would result in lack of class switch to IgG or IgA
Biology
1 answer:
sukhopar [10]3 years ago
3 0

Answer:

CD40L  

Explanation:

The CD40 ligand (CD40L) protein is a transmembrane glycoprotein which is expressed on activated T cells and belongs to the tumor necrosis factor (TNF) superfamily. The hyper IgM syndrome is caused by mutations in the CD40L gene, where the defective protein can no longer bind CD40 on antigen-presenting cells. The X-linked Hyper IgM syndrome is characterized by abnormal levels of immunoglobulins, i.e., low levels of IgG and IgA, and increased/normal levels of IgM. Because CD40L gene is located on the X chromosome, this disorder is observed much more frequently in males than in females.

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Cómo podría tu familia y tú manifestar su participación democrática en la sociedad y el
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Is the following statement true or false? the most frequent sign and symptom of a developing pulmonary embolus is tachypnea and
Rainbow [258]

The statement is True.

Dyspnea has a multi-factorial origin, resulting from bronchospasm or vasospasm, disturbances in pulmonary circulation, immobility or diminished respiratory excursion of the diaphragm, atelectasia and/or pulmonary infarction, anoxia, or impairment of cardiac function.

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6 0
2 years ago
The major buffer in blood is composed of the weak acid carbonic acid (H2CO3) and its conjugate base, bicarbonate ion (HCO3 - ).
tatuchka [14]

Answer:

The increase in the amount of  carbon dioxide in in blood will lead to respiratory acidosis

Explanation:

Carbon dioxide in its normal level between  38 to 42 mm Hg plays vital roles in the human body like regulating the PH of the human blood, breathing regulation and other things. If the amount of carbon dioxide is high more than the range level, it will cause what is called respiratory acidosis.

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6 0
3 years ago
46. The experiments that clearly showed that DNA from every organism studied had an amount of adenine equal to the amount of thy
Pepsi [2]

The given question number 48 is not complete, the complete question is:

Who utilized the process of transformation, as originally demonstrated by Frederick Griffith, to provide the first solid evidence suggesting that DNA was the genetic material of living systems (in this case bacteria)?

Messelson and Stahl

Thomas Morgan

Erwin Chargaff

Hershey and Chase

Avery, McCarty and Macleod

Answer:

The correct answer of 46 is option d, that is, Erwin Chargaff.

The correct answer of 47 is option c, that is, G0 phase.

The correct answer of 48 is option e, that is, Avery, McCarty and Macleod.

Explanation:

46. Erwin Chargaff with the help of an experiment demonstrated that the amount of adenine present within the DNA is always equivalent to the amount of thymine present, similarly, guanine is always found in equal number to cytosine. He also demonstrated that pairing is always done between pyrimidines and purines within the DNA.  

47. It is in the G0 stage, also known as the quiescent stage, where a human cell is found in the non-proliferating phase. It is also considered as the resting stage of the cell cycle in which cell gathers enough of the substances for its nourishment. When the cell moves into the G0 stage of the cell cycle, then the cell either goes to further stages of the cycle when needed or goes through the process of differentiation.  

48. To prove that DNA works as a genetic substance, the Griffith experiment was further used by Avery, McCarthy, and Macloed. The experiment was again performed on a biochemical basis. In the experiment, distinct constituents of the bacterial cell were digested with the assistance of digestive enzymes, and in the process, it was found that when digestion of DNA was done, the process of transformation failed to take place. The performed experiment was also called the biochemical assay of transformation.  

3 0
4 years ago
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