1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
tia_tia [17]
3 years ago
14

Anthony Hoffnagle was well until after 6 months of age when he was hospitalized for pneumonia 5 times in the same year. A consul

tation with an immunologist revealed normal numbers of B cells and T cells, slightly elevated IgM, and a marked decrease in IgG and IgA. He was diagnosed with X-linked hyper IgM syndrome. Based upon the information in the previous questions, what is the most important gene that might be defective that would result in lack of class switch to IgG or IgA
Biology
1 answer:
sukhopar [10]3 years ago
3 0

Answer:

CD40L  

Explanation:

The CD40 ligand (CD40L) protein is a transmembrane glycoprotein which is expressed on activated T cells and belongs to the tumor necrosis factor (TNF) superfamily. The hyper IgM syndrome is caused by mutations in the CD40L gene, where the defective protein can no longer bind CD40 on antigen-presenting cells. The X-linked Hyper IgM syndrome is characterized by abnormal levels of immunoglobulins, i.e., low levels of IgG and IgA, and increased/normal levels of IgM. Because CD40L gene is located on the X chromosome, this disorder is observed much more frequently in males than in females.

You might be interested in
Please help! Out of the 100 cells shown, how many are in the process of dividing?
nlexa [21]

Answer:

I think 7 cells are going to divide

3 0
3 years ago
Read 2 more answers
What method is water added to the atmosphere​
lubasha [3.4K]

Answer:

Transpiration

Explanation:

Heat from the Sun causes water to evaporate from the surface of lakes and oceans. This turns the liquid water into water vapor in the atmosphere. Plants, too, help water get into the atmosphere through a process called transpiration!

8 0
3 years ago
The large, flat bone extending from the middle of the back upward to the joint where it attaches to the clavicle is called the?
Daniel [21]

The large, flat bone extending from the middle of the back upward to the joint where it attaches to the clavicle is called the scapula.

Clavicle is the collar bone. It is a long and thin bone with slight curve that works to connect the arms to the body. It is a part of the shoulder. It allows free movement of the shoulder. The clavicle is attached with the sternum through the sternoclavicular joint.

Scapula is a triangular-shaped bone. it is present at the upper back portion. It us surrounded by various muscles that allow the free movement of the shoulder. The types of motion, scapula helps in are: protraction, retraction, elevation, depression, upward rotation, and downward rotation.

To know more about clavicle and scapula ,here

brainly.com/question/12926657

#SPJ4

6 0
2 years ago
HELP ME PLEASE PLEASE PLEASE
Korvikt [17]

Answer:

<h3>mitosis</h3>

Explanation:

the cell divison which gives 2 daughter cells from one parent cell is mitosis it takes place in body cromosomes or in autosomal or in somatic cells

3 0
3 years ago
Oxygen starvation in a cell will most likely lead to
Scrat [10]
The answer to this question would be: necrosis

Necrosis is the death of cell caused by various injury, one of them is oxygen starvation. Cells need a constant supply of energy to sustain its life. Without oxygen, the energy produced by cells will be decreased. When the energy is depleted, the cell will not be able to use ion pumps or any organelle that need energy. This will slowly damage the cell until it dies.
6 0
3 years ago
Read 2 more answers
Other questions:
  • How are archaea and bacteria alike?
    11·2 answers
  • A microscope technique that will not allow one to see specific parts of living specimen is
    8·1 answer
  • FRAP has revealed that some proteins move in cell membranes much slower than they move in reconstituted liposomes. Which of the
    10·1 answer
  • True Or False? the total amount of matter on earth changes significantly over geological time scales, roughly every 300,000,000
    11·1 answer
  • My parents are too hard on me to get good grades and it stresses me out. Help!
    6·2 answers
  • Explain what would occur if the population of an animal such as a beaver, changes the environment and can increase the number of
    15·1 answer
  • 2. How does temperature describe motion?
    14·2 answers
  • Which diagram shows photosynthesis with the correct reactants and products?
    13·1 answer
  • How greenhouse gases can lead to the formation of damaging acid rain
    9·1 answer
  • low-density expansion protects human synovium-derived stem cells from replicative senescence: a preliminary study
    15·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!