1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
tia_tia [17]
3 years ago
14

Anthony Hoffnagle was well until after 6 months of age when he was hospitalized for pneumonia 5 times in the same year. A consul

tation with an immunologist revealed normal numbers of B cells and T cells, slightly elevated IgM, and a marked decrease in IgG and IgA. He was diagnosed with X-linked hyper IgM syndrome. Based upon the information in the previous questions, what is the most important gene that might be defective that would result in lack of class switch to IgG or IgA
Biology
1 answer:
sukhopar [10]3 years ago
3 0

Answer:

CD40L  

Explanation:

The CD40 ligand (CD40L) protein is a transmembrane glycoprotein which is expressed on activated T cells and belongs to the tumor necrosis factor (TNF) superfamily. The hyper IgM syndrome is caused by mutations in the CD40L gene, where the defective protein can no longer bind CD40 on antigen-presenting cells. The X-linked Hyper IgM syndrome is characterized by abnormal levels of immunoglobulins, i.e., low levels of IgG and IgA, and increased/normal levels of IgM. Because CD40L gene is located on the X chromosome, this disorder is observed much more frequently in males than in females.

You might be interested in
The efficiency of a car’s engine is 14 percent. This implies that the engine wastes
Harlamova29_29 [7]

Answer:

C) 86 J of energy for every 100 J that enter it.  

Explanation:

Efficiency is a measure of performance of an engine which can be calculated by the formula as given below to get in percentage:

           Efficiency = energy output/energy input x 100

If the efficiency of a car’s engine is 14 percent it means that for every 100 joules of energy that is entered into it, only 14 joule is converted into useful output and rest of the 86 Joules is wasted.

The efficiency of any machine is never 100%, however, if any machine miraculously converts all the input energy to useful output energy, it means it is 100% efficient.

Hope it helps!


7 0
3 years ago
What is the branch of science that is concerned with the way in which the organism and its parts function?
alexira [117]
Either biology or anatomy 
4 0
3 years ago
Read 2 more answers
One principle reason cells are so small is so that
Tom [10]
I would select A because cells have to divide into smaller cells depending on where they are.
7 0
2 years ago
Read 2 more answers
2.4 Explain the safety measures that one should consider when participating in physical education activities. ​
Alex17521 [72]
One should consider: proper clothing and shoes-so not to get injured. Knowledge of equipment and activity—one should know how to use all equipment and know how to play the games/activity so not to hurt themselves or others. Proper hydration and nutrition before hand-so not to get dehydrated or dizzy or sick and safety og equipment and location-check for broken items and discard, check environment for hills, holes, sticks, traffic, etc.
5 0
3 years ago
"Adaptations develop in response to environmental changes. For example, if a human population was displaced into the ocean, even
mel-nik [20]

Answer:

uh Photoperiodism

Explanation:

3 0
2 years ago
Other questions:
  • What is the name of the bond that is created when two amino acids join? hydrogen bond
    11·2 answers
  • During a standing pulling assessment, a client compensates by moving his head forward. Which of the following static stretches w
    8·1 answer
  • What is the relationship between the bud and the parent
    14·2 answers
  • This is so I don't fail. Please help! I have a lot of questions and am willing to give a lot of points.
    13·2 answers
  • Which sexually transmitted infection has recently been implicated as a risk factor for coronary artery disease?HPV infectionHIV
    14·1 answer
  • Describe how tissue fluid and lymph fluid form and explain lymph function​
    10·1 answer
  • Write mechanism of absorption​
    13·2 answers
  • If radioactive Forcing were to increase in a particular region of earth what would you expect to happen to average temperatures
    15·1 answer
  • How does the nuclear envelope aide in compartmentalization? All but ONE apply.
    11·1 answer
  • The processes of megakaryocytes from which platelets are derived, extend between endothelial cells of blood vessels and are call
    12·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!