1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Lerok [7]
2 years ago
9

A group of scientists were using CRISPR to treat a mouse with cystic fibrosis, a disease caused by a defective Cl- channel prote

in called CFTR. The most common cause of cystic fibrosis in humans is the absence of a phenylalanine, an amino acid, in the CFTR protein, which prevents CFTR from achieving the correct 3-D structure.If the scientists wished to repair this mutation, how would they alter the mutated CFTR gene before using CRISPR to insert the DNA into the mice
Biology
1 answer:
love history [14]2 years ago
6 0

Answer:

they can insert the codon that encodes phenylalanine by CRISPR-Cas mediated homology-directed repair

Explanation:

The CRISPR (clustered regularly interspaced short palindromic repeats,)-Cas (CRISPR-associated protein) is a versatile technology for genome editing which has been developed by adapting a natural defense mechanism found in prokaryotic organisms. The CRISPR-Cas genome editing tool can be used to edit DNA sequences in eukaryotic genomes (for example, in human genomes) and thus restore gene function (in this case, the CFTR gene function). The system consists of a Cas protein that cleaves the DNA at specific genomic sites and a single guide RNA (sgRNA) that guides the Cas protein at specific genomic locations. CRISPR-Cas mediated homology-directed repair refers to the process where Cas cuts the DNA to triggers the homologous recombination (HR) DNA repair pathway, by which it is possible to insert new genetic sequences at specific genomic sites (in this case, the codon that encodes phenylalanine within the specific CFTR gene).

You might be interested in
What is one reason why the classification of protists in one kingdom is difficult?
Aleksandr-060686 [28]

B.  Protists more closely resemble members of other eukaryotic kingdoms than they do other protists.

Explanation:

It is difficult for scientists to classify protists into one kingdom because they closely resemble member of other eukaryotic kingdoms than they do other protists.

The protists have a wide variations among themselves that makes them very difficult to classify.

  • Protists have a wide-range of diversity within them and they flaunt every rule used to classify them.
  • Protists have also shown characteristics of different kingdoms between them.

learn more:

Kingdom of life brainly.com/question/5186929

#learnwithBrainly

7 0
3 years ago
Why is my goldfish floating on top of the water and not swimming. (My mom took it away from me and she won't tell me)
mars1129 [50]

Answer: your goldfish is in fish heaven now

5 0
2 years ago
Read 2 more answers
Word bank: phenotype, genotype, heterozygous, homozygous, traits,
posledela

Answer:

what's this for

Explanation:

?????????????÷&÷÷&

5 0
3 years ago
Camille and her friends enjoy experimenting with different foods. During a camping trip, they decide to fry bacon using nothing
natima [27]
<span>The two sentences that accurately describe the girls' experience with heat transfer are "Camille heats a rock in the campfire for 30 minutes, and then removes it with tongs. She greases the rock and lays the bacon strips directly on it." By heating the rocks in the campfire and laying the bacon on the rocks, the girls transferred the heat from the fire to the rocks, and the heat from the rocks to cook the bacon.</span>
7 0
3 years ago
Read 2 more answers
What factors can affect an organisms trait
Artemon [7]

Answer:

Environmental factors such as diet, temperature, oxygen levels, humidity, light cycles, and the presence of mutagens can all impact which of an animal's genes are expressed, which ultimately affects the animal's phenotype.

Explanation:

3 0
2 years ago
Other questions:
  • The movement of carbohydrates throughout a plant is called translocation.<br><br> True<br> False
    10·1 answer
  • Match each step of the scientific method with its description
    5·1 answer
  • Identify the Main Idea In your own words, describe what a Punnet
    5·1 answer
  • What term describes the early kind of biologists that made and recorded observations about organisms in natures
    15·2 answers
  • A nerve cell with normal levels of intracellular calcium is treated with intracellular IP3, which opens calcium channels in the
    14·1 answer
  • Most enzymes
    8·1 answer
  • Which choice describes the thyroid?
    9·1 answer
  • Why is cell called the fundamental unit of life ​
    11·2 answers
  • Life After People (Vicious Reptiles Conquer the Planet)?
    12·1 answer
  • The two DNA strands are held together by ____________ bonding between the bases on the different strands; therefore, all the bas
    15·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!