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omeli [17]
3 years ago
10

In the ovary, oocytes are held at metaphase II of meiosis until fertilization. How is this

Biology
1 answer:
aleksandr82 [10.1K]3 years ago
8 0

Answer:

Progesterone activates C-Mos, which phosphorylates maturation promotion factor (MPF)

Explanation:

Progesterone is a steroid hormone that is well known to be involved in embryogenesis, which is secreted by the corpus luteum. During meiosis I, steroid production is limited to progesterone. Moreover, the oocyte maturation factor Mos (cMOS) is kinase expressed in germ-line cells when it is activated by progesterone, where this factor controls oocyte maturation and the arrest at the metaphase of meiosis II by modulating the activity of the Maturation-promoting factor (MPF). This protein (MPF) is a cyclin-dependent kinase complex that promotes mitotic entry via phosphorylation of different proteins required during mitosis.

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