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A Multi-Celled organism has many cells (more than one). Examples would be plants, humans and animals/mammals.
A Single-Celled organism only has one cell that makes up it's entire self. Examples would be bacteria and archaea.
If a major change in pH occurred, the protease enzymes would stop functioning or function very slowly, assuming the original pH was the most optimal pH for them.
Explanation:
Thermophilic bacteria: a new cause of human disease. ... These bacteria are all gram-negative, nonfermentative, nonsporulating rods, most of which grow better at 42 or 50 degrees C than at 35 degrees C. Some of the bacteria could be implicated as the etiological agents for meningitis, endocarditis, and septicemia.